Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27225814 | 0.99 | CNR1 (0.47) | CNR1CNR2HDAC1HDAC2PLA2G4B | |
| SCHEMBL24675243 | 0.95 | PLA2G4B (0.46) | CNR1CNR2HDAC1HDAC2PLA2G4B | |
| Hydrochloric Acid SCHEMBL25290504 | 0.94 | PLA2G4B (0.46) | HDAC1HDAC2PLA2G4BFFAR1CYSLTR2 | |
| SCHEMBL24675655 | 0.88 | FFAR1 (0.49) | PLA2G4BFFAR1FFAR4CFD | |
| SCHEMBL24675865 | 0.88 | FFAR1 (0.49) | PLA2G4BFFAR1FFAR4CFD | |
| SCHEMBL25822896 | 0.87 | PLA2G4B (0.49) | HDAC1HDAC2PLA2G4BFFAR1PPARA | |
| SCHEMBL24675766 | 0.86 | CNR1 (0.47) | CNR1CNR2HDAC1HDAC2PLA2G4B | |
| SCHEMBL25823996 | 0.86 | CNR1 (0.47) | CNR1CNR2HDAC1HDAC2PLA2G4B | |
| SCHEMBL24675794 | 0.86 | CNR1 (0.47) | CNR1CNR2HDAC1HDAC2PLA2G4B | |
| Hydrochloric Acid SCHEMBL25250931 | 0.86 | PLA2G4B (0.48) | HDAC1HDAC2PLA2G4BFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022159688-A9 | DEGRADERS OF GRK2 AND USES THEREOF | SONATA THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2022159688-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2022-07-28 | — | — | WO | disclosed |