SCHEMBL25823294

SCHEMBL25823294

CC(C)(C)Cc1cccc(C2CCC(=O)NC2=O)c1

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.63
DDB1 Q16531 18/20 0.63
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24548293 0.85 CRBN (0.60) CRBNDDB1POLB
SCHEMBL24548362 0.85 CRBN (0.63) CRBNDDB1POLB
SCHEMBL25822350 0.83 CRBN (0.65) CRBNDDB1POLB
SCHEMBL24754148 0.82 CRBN (0.59) CRBNDDB1POLB
SCHEMBL26641343 0.80 CRBN (0.60) CRBNDDB1POLB
SCHEMBL30643548 0.80 CRBN (0.60) CRBNDDB1POLB
SCHEMBL25818978 0.80 CRBN (0.63) CRBNDDB1POLB
SCHEMBL24548260 0.77 CRBN (1.00) CRBNDDB1POLB
SCHEMBL21934060 0.77 CRBN (0.68) CRBNDDB1POLB
SCHEMBL30643581 0.77 CRBN (0.56) CRBNDDB1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125944-A1 COMPOUND CONTAINING HETEROCYCLIC RING 正大天晴药业集团股份有限公司 2023-07-06 WO disclosed