Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822728 | 0.83 | SYK (0.55) | SYKCD63 | |
| SCHEMBL25822684 | 0.79 | SYK (0.57) | SYKCD63 | |
| SCHEMBL25823831 | 0.75 | SYK (0.49) | SYKCD63 | |
| SCHEMBL16848683 | 0.72 | SYK (0.68) | SYKCD63 | |
| SCHEMBL25822732 | 0.72 | SYK (0.48) | SYKCD63 | |
| SCHEMBL25822712 | 0.71 | MAPT (0.58) | SYKCD63 | |
| SCHEMBL16851493 | 0.68 | SYK (0.71) | SYKCD63 | |
| SCHEMBL15551918 | 0.68 | SYK (0.69) | SYKCD63 | |
| SCHEMBL28564010 | 0.68 | SYK (0.69) | SYKCD63 | |
| SCHEMBL25822735 | 0.68 | MAPKAPK5 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219960-A1 | 1H-PYRAZOLE DERIVATIVE AND APPLICATION THEREOF AS DUAL TARGET INHIBITOR OF SYK AND VEGFR2 | OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219960-A1 | 1H-PYRAZOLE DERIVATIVE AND APPLICATION THEREOF AS DUAL TARGET INHIBITOR OF SYK AND VEGFR2 | SYK, KDR, FLT1 | SYK 1/4885CD63 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.