SCHEMBL258234

SCHEMBL258234

OC1(O)C=Cc2ccccc2C1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
MAOB P27338 2/20 0.34
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31520302 1.00 PARP1 (0.36) PARP1CA1CA2MAOBGAA
SCHEMBL23781284 0.79 PARP1 (0.34) PARP1CA1CA2MAOB
SCHEMBL8351271 0.79 PARP1 (0.34) PARP1CA1CA2
SCHEMBL2151230 0.79 PARP1 (0.34) PARP1CA1CA2
SCHEMBL2288761 0.77 PARP1 (0.39) PARP1CA1CA2MAOBGAA
SCHEMBL31442138 0.76 HDAC9 (0.35) PARP1CA1CA2
SCHEMBL5734197 0.75 CA1 (0.32) PARP1CA1CA2
SCHEMBL9793274 0.75 CA1 (0.32) PARP1CA1CA2MAOB
SCHEMBL7529245 0.75 CA1 (0.35) PARP1CA1CA2MAOB
SCHEMBL1697644 0.74 PARP1 (0.36) PARP1CA1CA2MAOBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3700957-A2 RESIN COMPOSITIONS AND RESIN INFUSION PROCESS Cytec Industries Inc. (US) 2020-09-02 EP claimed
US-9142328-B2 Molecule for functionalizing a support, attachment of a radionuclide to the support and radionuclide generator for preparing the radionuclide, and preparation process ITM Isotopen Technologien München AG (DE) 2015-09-22 US claimed
EP-2092018-A1 LOW ODOR, FAST CURE, TOUGHENED EPOXY ADHESIVE Ashland Licensing and Intellectual Property LLC (US) 2009-08-26 EP claimed
EP-2032625-A1 MANUFACTURE OF POLYCARBONATES Sabic Innovative Plastics IP B.V. (NL) 2009-03-11 EP claimed
US-7495064-B2 Manufacture of polycarbonates SABIC INNOVATIVE PLASTICS IP BV (NL) 2009-02-24 US claimed
EP-2021761-A1 SAMPLING DEVICE Provtagaren Ab (SE) 2009-02-11 EP claimed
EP-2001924-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS National Starch and Chemical Investment Holding Corporation (US) 2008-12-17 EP claimed
WO-2008076211-A1 LOW ODOR, FAST CURE, TOUGHENED EPOXY ADHESIVE ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC (US) 2008-06-26 WO claimed
EP-1740640-A4 DIBENZODIAZOCINE POLYMERS SOLVAY ADVANCED POLYMERS LLC (US) 2008-06-04 EP claimed
WO-2008002721-A1 MANUFACTURE OF POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-03 WO claimed
EP-1492766-A1 IMPROVED CC-1065 ANALOG SYNTHESIS Immunogen, Inc. (US) 2005-01-05 EP claimed
WO-2003087190-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-10-23 WO claimed
WO-2003087055-A1 IMPROVED CC-1065 ANALOG SYNTHESIS IMMUNOGEN, INC. (US) 2003-10-23 WO claimed
WO-2003074016-A1 METHOD OF GRADUAL PERMANENT COLORING OF HAIR UNILEVER PLC (GB) 2003-09-12 WO claimed
WO-2003055458-A1 GRADUAL PERMANENT COLORING OF HAIR USING DYE INTERMEDIATES IN A SHAMPOO BASE UNILEVER PLC (GB) 2003-07-10 WO claimed
WO-2003055457-A1 GRADUAL PERMANENT COLORING OF HAIR USING DYE INTERMEDIATES IN A SHAMPOO BASE UNILEVER PLC (GB) 2003-07-10 WO claimed
WO-2003035941-A2 ELECTROLYTIC PROCESSES WITH REDUCED CELL VOLTAGE AND GAS FORMATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-05-01 WO claimed
WO-2000022662-A1 INHIBITION OF TITANIUM CORROSION EKC TECHNOLOGY, LTD (GB) 2000-04-20 WO claimed
WO-1998034601-A2 METHOD FOR INHIBITING INTRACELLULAR VIRAL REPLICATION CELL THERAPEUTICS, INC. (US) 1998-08-13 WO claimed
WO-1995022576-A1 ADHESION SYSTEM BEAVER MANUFACTURING COMPANY, INC. (US) 1995-08-24 WO claimed