SCHEMBL7529245

SCHEMBL7529245

O=C(O)C1(O)C=Cc2ccccc2C1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PARP1 P09874 1/20 0.32
AKR1C1 Q04828 1/20 0.32
CXCR5 P32302 2/20 0.31
SRD5A2 P31213 2/20 0.31
SRD5A1 P18405 1/20 0.31
HSD17B3 P37058 1/20 0.31
MME P08473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10903875 0.82 CXCR5 (0.45) PARP1CXCR5
SCHEMBL28648656 0.80 MEN1 (0.36) CA1CA2
SCHEMBL11626153 0.80 MAOB (0.36) CA1CA2MAOBHDAC9PARP1
SCHEMBL8068895 0.80 MAOA (0.35) CA1CA2MAOAMAOBHDAC9
SCHEMBL28680139 0.78 ESR1 (0.36) CA1CA2
SCHEMBL16487137 0.78 PTPRC (0.34) CA1CA2MAOAMAOB
SCHEMBL27576291 0.78 DDB1 (0.44) TDP1
SCHEMBL4734678 0.77 MAOA (0.33) CA1CA2MAOAMAOBHDAC9
SCHEMBL10393568 0.77 BRD4 (0.45)
SCHEMBL258234 0.75 PARP1 (0.36) CA1CA2MAOBPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0490300-B1 Process for the production of surface-modified electrophotographic toner particles NIPPON PAINT CO LTD (JP) 1998-03-25 EP claimed
US-5190844-A Electrophotographic toner NIPPON PAINT CO., LTD. (JP) 1993-03-02 US claimed
EP-0490300-A1 Production of surface-modified organic particles Nippon Paint Co., Ltd. (JP) 1992-06-17 EP claimed
JP-62169862-A None JP disclosed
CN-113348165-A 1,2, 4-triazin-3 (2H) -one compounds for the treatment of hyperproliferative diseases 拜耳股份有限公司 2021-09-03 CN disclosed
CN-112939764-A Production process of 2-hydroxy-3-naphthoic acid 宿迁思睿屹新材料有限公司 2021-06-11 CN disclosed
CN-1737682-B Planographic printing plate precursor FUJI PHOTO FILM CO LTD 2011-01-19 CN disclosed
CN-1737682-A Planographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-02-22 CN disclosed
CN-1688549-A Compound having TGF-beta inhibitory activity and medicinal composition containing the same KIRIN BREWERY (JP) 2005-10-26 CN disclosed
US-20020061964-A1 Thermoplastic resin composition and molding thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-23 US disclosed
US-5955002-A Method for determining properties of a polymer coating or film cured by cationic polymerization SPECTRA GROUP LIMITED, INC. (US) 1999-09-21 US disclosed
EP-0149172-B1 FLUORINATED QUATERNARY AMMONIUM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS DRAG REDUCING AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-12-07 EP disclosed
US-4758636-A Polyester composition POLYPLASTICS COMPANY, LTD. (JP) 1988-07-19 US disclosed
EP-0231606-A2 Polyester composition POLYPLASTICS CO. LTD. (JP) 1987-08-12 EP disclosed
JP-S62169862-A PRODUCTION OF AZO PIGMENT SUMITOMO CHEM CO LTD 1987-07-27 JP disclosed
EP-0226361-A1 Electrically conductive resin composition POLYPLASTICS CO. LTD. (JP) 1987-06-24 EP disclosed
EP-0214827-A2 Surface-metallized, moulded resin article POLYPLASTICS CO. LTD. (JP) 1987-03-18 EP disclosed
EP-0184367-A1 Process for producing electroconductive resin composite POLYPLASTICS CO. LTD. (JP) 1986-06-11 EP disclosed
EP-0149172-A1 Fluorinated quaternary ammonium compounds, processes for their preparation and their use as drag reducing agents HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-24 EP disclosed
US-4195973-A Process for printing with developing dyes which employs having ether substituents derived from glycols, polyglycols, or alkoxy derivatives thereof HOECHST AKTIENGESELLSCHAFT (DE) 1980-04-01 US disclosed