Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 20/20 | 0.69 |
| ▸ | KRAS | P01116 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24096437 | 0.94 | SOS1 (0.77) | SOS1KRASCYP3A4CYP2C8CYP2D6 | |
| SCHEMBL25296369 | 0.94 | SOS1 (0.77) | SOS1KRASCYP3A4CYP2C8CYP2D6 | |
| SCHEMBL25823751 | 0.83 | SOS1 (0.64) | SOS1KRAS | |
| SCHEMBL23326445 | 0.82 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL23326442 | 0.82 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL25823842 | 0.80 | SOS1 (0.61) | SOS1KRAS | |
| SCHEMBL23326372 | 0.79 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL23326371 | 0.79 | SOS1 (1.00) | SOS1KRAS | |
| SCHEMBL25141081 | 0.78 | SOS1 (0.55) | SOS1KRASCYP3A4CYP2C8CYP2D6 | |
| SCHEMBL23411941 | 0.78 | SOS1 (0.69) | SOS1KRASCYP3A4CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219951-A1 | PYRIDINE-PYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219951-A1 | PYRIDINE-PYRIMIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | WEE1, SOS1, HINT1 | SOS1 2/4885KRAS 297/4885CYP3A4 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.