Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 3/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | AMD1 | P17707 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577461 | 0.78 | TLR7 (0.52) | TLR7NSD3PI4KAPI4K2BPI4K2A | |
| SCHEMBL25457076 | 0.75 | CDK1 (0.36) | TLR7PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24420709 | 0.75 | TLR7 (0.46) | TLR7NSD3PI4KAPI4K2BPI4K2A | |
| SCHEMBL15079240 | 0.70 | RXFP1 (0.36) | LMNA | |
| SCHEMBL22560001 | 0.69 | PNP (0.43) | ALDH1A1KDM4EHPGD | |
| SCHEMBL10149394 | 0.68 | DAO (0.39) | — | |
| SCHEMBL23803929 | 0.68 | ADORA3 (0.49) | TLR7PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13850509 | 0.68 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL19945800 | 0.67 | TLR7 (0.60) | TLR7NSD3NSD2NUDT1ALDH1A1 | |
| SCHEMBL31626196 | 0.66 | SRC (0.48) | TLR7RETSRCABL1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |