Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669756 | 0.80 | HRH3 (0.43) | HRH3HTR2AOPRD1DRD2KDM4E | |
| SCHEMBL12391503 | 0.78 | MAPT (0.45) | HRH3CYP2C9NPC1MAPT | |
| SCHEMBL25814892 | 0.78 | SIGMAR1 (0.44) | HRH3EPHX2CYP2C9HTR2ATRPM8 | |
| SCHEMBL2348744 | 0.77 | AKT1 (0.46) | HRH3EPHX2HTR2AHDAC3HDAC4 | |
| SCHEMBL1690952 | 0.77 | HTR2A (0.50) | HRH3EPHX2HTR2ATRPM8OPRD1 | |
| SCHEMBL4220742 | 0.77 | HTR2C (0.49) | HRH3EPHX2CYP2C9HTR2AOPRD1 | |
| SCHEMBL5321592 | 0.77 | HTR2C (0.46) | HRH3HTR2AHDAC3HDAC4HDAC1 | |
| SCHEMBL1813821 | 0.76 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Hydrochloric Acid SCHEMBL4221293 | 0.76 | HTR2C (0.48) | HRH3EPHX2CYP2C9HTR2AOPRD1 | |
| Hydrochloric Acid SCHEMBL8567312 | 0.75 | HTR2A (0.56) | HRH3HTR2AOPRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |