Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25324670 | 0.83 | HTR2A (0.31) | HTR2A | |
| SCHEMBL23043635 | 0.81 | MEN1 (0.43) | TAAR1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL25824422 | 0.81 | AKR1B1 (0.37) | HTR2AALDH1A1GABRA1GABRB2KDM4E | |
| SCHEMBL23043189 | 0.79 | HTR2A (0.40) | HTR2ATAAR1ALDH1A1TSHRGABRA1 | |
| SCHEMBL31733104 | 0.79 | HTR2A (0.40) | HTR2ATAAR1ALDH1A1TSHRGABRA1 | |
| SCHEMBL23043698 | 0.79 | NQO2 (0.34) | HTR2ATAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL31245544 | 0.79 | TAAR1 (0.54) | TAAR1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL2541735 | 0.79 | TAAR1 (0.54) | TAAR1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL25824423 | 0.79 | HTR2A (0.33) | HTR2AHTR2C | |
| SCHEMBL27779739 | 0.78 | CYP2A6 (0.32) | HTR2ATAAR1IDO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |