SCHEMBL25824708

SCHEMBL25824708

Cc1c(Br)oc2cccc(Cl)c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
PSMB8 P28062 1/20 0.35
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
TTR P02766 3/20 0.33
AHR P35869 2/20 0.33
KDM1A O60341 1/20 0.33
ELANE P08246 2/20 0.33
PBRM1 Q86U86 1/20 0.32
PARP1 P09874 1/20 0.32
HRH4 Q9H3N8 1/20 0.31
DHODH Q02127 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22884332 0.71 ELANE (0.41) PSMB8TTRAHRELANEMEN1
SCHEMBL29658023 0.71 ELANE (0.41) PSMB8TTRAHRELANEMEN1
SCHEMBL19802418 0.68 AHR (0.45) ALDH1A1TTRAHRELANEHRH4
SCHEMBL4449379 0.68 KDM4E (0.46) ALDH1A1KMT2A
SCHEMBL28650143 0.68 GAA (0.35) ALDH1A1PSMB8TTRAHRELANE
SCHEMBL11097183 0.67 KDM1A (0.43) ALDH1A1TTRKDM1ADHODHMEN1
SCHEMBL15998121 0.67 MAOA (0.36) ALDH1A1AHRMEN1KMT2ACYP1A2
SCHEMBL443037 0.66 TSHR (0.41) ALDH1A1PSMB8TTRAHRELANE
SCHEMBL19656483 0.65 AHR (0.54) PSMB8TTRAHRELANECYP1A2
SCHEMBL29853208 0.65 KCNA3 (0.37) ALDH1A1PSMB8TTRAHRELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132488-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-13 WO disclosed