SCHEMBL25824805

SCHEMBL25824805

Cc1cc(C)c(-n2c3ccccc3c(=O)c3cc4c(cc32)c(=O)c2ccccc2n4-c2cc(C)c(C)c(C)c2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 10/20 0.37
P2RX4 Q99571 1/20 0.37
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MARK4 Q96L34 2/20 0.36
DPP4 P27487 1/20 0.36
TP53 P04637 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
CRHR1 P34998 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752454 0.90 P2RX4 (0.43) ABCB1P2RX4MAPTSMN1; SMN2NPC1
SCHEMBL25824806 0.88 MARK4 (0.32) MAPTSMN1; SMN2MARK4DPP4
SCHEMBL25824807 0.86 DPP4 (0.34) MAPTDPP4CRHR1ALDH1A1
SCHEMBL25752406 0.83 MAPT (0.46) ABCB1P2RX4MAPTSMN1; SMN2MARK4
SCHEMBL18830657 0.78 CYP1A2 (0.42) MAPTSMN1; SMN2DPP4CRHR1ALDH1A1
SCHEMBL25752455 0.77 NPSR1 (0.38) ABCB1P2RX4MARK4DPP4NPC1
SCHEMBL25752369 0.77 P2RX4 (0.51) P2RX4MAPTSMN1; SMN2MARK4TP53
SCHEMBL13991584 0.76 CYP1A2 (0.47) ABCB1MAPTSMN1; SMN2DPP4NPC1
SCHEMBL12127982 0.76 KDM4E (0.56) MAPTSMN1; SMN2ALDH1A1
SCHEMBL25752457 0.75 LMNA (0.36) ABCB1MAPTDPP4CRHR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed