Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27057906 | 0.89 | TLR7 (0.51) | TLR7NSD3NSD2ALDH1A1 | |
| SCHEMBL25824839 | 0.87 | TLR7 (0.45) | TLR7NSD3NSD2TLR8ALDH1A1 | |
| SCHEMBL25823816 | 0.83 | TLR7 (0.46) | TLR7NSD3NSD2ALDH1A1 | |
| SCHEMBL25826053 | 0.82 | TLR7 (0.46) | TLR7NSD3NSD2TLR8 | |
| SCHEMBL24420709 | 0.71 | TLR7 (0.46) | TLR7NSD3NSD2ALDH1A1 | |
| SCHEMBL6577461 | 0.71 | TLR7 (0.52) | TLR7NSD3NSD2ALDH1A1 | |
| SCHEMBL27057898 | 0.68 | TLR7 (0.46) | TLR7NSD3NSD2ALDH1A1 | |
| SCHEMBL25457796 | 0.68 | CDK1 (0.36) | TLR7ALDH1A1 | |
| SCHEMBL14642161 | 0.67 | KDM4D (0.45) | — | |
| SCHEMBL21090693 | 0.66 | PI4KA (0.67) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |