Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 6/20 | 0.52 |
| ▸ | DNMT3A | Q9Y6K1 | 5/20 | 0.52 |
| ▸ | DNMT3L | Q9UJW3 | 2/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19151335 | 0.93 | MAPT (0.82) | KMT2AMAPTUSP2POLBMAPK1 | |
| SCHEMBL30180657 | 0.93 | MAPT (0.82) | KMT2AMAPTUSP2POLBMAPK1 | |
| SCHEMBL13335886 | 0.91 | KMT2A (0.85) | KMT2AMAPTUSP2POLBMAPK1 | |
| SCHEMBL25825409 | 0.87 | DNMT1 (0.57) | KMT2AMAPTUSP2KDM4EALDH1A1 | |
| SCHEMBL13335884 | 0.86 | MAPT (0.77) | KMT2AMAPTUSP2POLBMAPK1 | |
| SCHEMBL13335888 | 0.86 | KMT2A (0.74) | KMT2AMAPTUSP2POLBMAPK1 | |
| SCHEMBL25825412 | 0.85 | DNMT1 (0.55) | KMT2AMAPTUSP2POLBDNMT1 | |
| SCHEMBL25826240 | 0.84 | KMT2A (0.57) | KMT2AMAPTUSP2POLBMAPK1 | |
| SCHEMBL25825376 | 0.84 | KMT2A (0.68) | KMT2AMAPTUSP2POLBMAPK1 | |
| SCHEMBL25825406 | 0.83 | DNMT1 (0.53) | KMT2AMAPTUSP2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | KMT2A 3974/4885MAPT 3999/4885USP2 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.