Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898935 | 0.98 | CYP19A1 (0.47) | CYP19A1ESRRGCA2CA9S1PR1 | |
| SCHEMBL12377326 | 0.86 | PTGS2 (0.46) | CYP19A1CA2CA9NPC1RAB9A | |
| SCHEMBL11965518 | 0.84 | FLT3 (0.46) | CYP19A1CA2CA9NPC1RAB9A | |
| SCHEMBL9729950 | 0.82 | PTGS2 (0.46) | CYP19A1CA2CA9NPC1RAB9A | |
| SCHEMBL12377290 | 0.82 | CYP19A1 (0.62) | CYP19A1CA2CA9NPC1RAB9A | |
| SCHEMBL9963176 | 0.81 | CYP19A1 (0.66) | CYP19A1CA2CA9NPC1RAB9A | |
| SCHEMBL25820297 | 0.80 | CYP19A1 (0.51) | CYP19A1ESRRGLRRK2 | |
| SCHEMBL23329321 | 0.80 | ESRRG (0.46) | CYP19A1ESRRGS1PR1NPC1RAB9A | |
| SCHEMBL16406113 | 0.79 | CYP19A1 (0.42) | CYP19A1CA2CA9LRRK2 | |
| SCHEMBL21286180 | 0.79 | CYP19A1 (0.42) | CYP19A1RAB9ATP53KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | CYP19A1 731/4885ESRRG 714/4885CA2 3030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.