Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094507 | 0.85 | AHR (0.44) | NAMPTAHRSCN5ANPC1ALDH1A1 | |
| SCHEMBL798670 | 0.81 | NAMPT (0.43) | NAMPTAHRDYRK1ANPC1ALDH1A1 | |
| SCHEMBL22790591 | 0.77 | SCN10A (0.38) | SCN10AAHRCYP11B2SCN5AMAP3K5 | |
| SCHEMBL15294468 | 0.77 | DYRK1A (0.36) | SCN10AAHRTMEM97SIGMAR1CYP11B2 | |
| SCHEMBL20088501 | 0.77 | NAMPT (0.43) | NAMPTAHRDYRK1ACSNK1DNPC1 | |
| SCHEMBL10220047 | 0.76 | AHR (0.47) | NAMPTAHRNPC1ALDH1A1RAB9A | |
| SCHEMBL20759311 | 0.76 | LMNA (0.38) | SCN10AAHRCYP11B2SCN5AMAP3K5 | |
| SCHEMBL21929912 | 0.76 | AHR (0.53) | NAMPTAHRDYRK1ANPC1ALDH1A1 | |
| SCHEMBL25825583 | 0.75 | PDE10A (0.32) | NAMPTAHR | |
| SCHEMBL6900236 | 0.68 | JAK2 (0.46) | NAMPTCYP11B2NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | NAMPT 1325/4885SCN10A 2866/4885AHR 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.