Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.48 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791787 | 0.82 | ALDH1A1 (0.49) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 | |
| SCHEMBL4793255 | 0.79 | GAA (0.44) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 | |
| SCHEMBL4794180 | 0.79 | ALDH1A1 (0.46) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 | |
| SCHEMBL48934 | 0.78 | SMN1; SMN2 (0.68) | GAAADCY8SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10330271 | 0.77 | GAA (0.53) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 | |
| SCHEMBL4794185 | 0.76 | GAA (0.43) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 | |
| SCHEMBL6564214 | 0.76 | GAA (0.59) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 | |
| Monoethanolamine SCHEMBL4793171 | 0.75 | GAA (0.42) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 | |
| SCHEMBL14621230 | 0.74 | GAA (0.57) | GAASMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL3754279 | 0.73 | GAA (0.50) | GAAKCNJ6KCNJ5KCNJ3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| CN-113024563-B | Pyrimido five-membered heterocyclic compound or pharmaceutically acceptable salt and isomer thereof, and preparation method, pharmaceutical composition and application thereof | 药康众拓(江苏)医药科技有限公司 | 2023-01-03 | — | — | CN | disclosed |