Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | ACACB | O00763 | 3/20 | 0.41 |
| ▸ | ACACA | Q13085 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1844407 | 0.94 | ACACB (0.42) | GPR119ACACBACACAPPARGPPARD | |
| SCHEMBL1842786 | 0.93 | ACACB (0.47) | GPR119ACACBACACAPPARGPPARD | |
| SCHEMBL2578258 | 0.91 | GPR119 (0.41) | GPR119ACACBACACAPPARGPPARD | |
| SCHEMBL2568194 | 0.90 | GPR119 (0.49) | GPR119HRH3 | |
| SCHEMBL2559912 | 0.87 | GPR119 (0.40) | GPR119ACACBACACAPPARGPPARD | |
| SCHEMBL2218214 | 0.86 | ACACB (0.41) | GPR119ACACBACACANPC1RAB9A | |
| SCHEMBL1842388 | 0.85 | GPR119 (0.42) | GPR119ACACBACACAPPARGPPARD | |
| SCHEMBL2216309 | 0.85 | ACACB (0.46) | GPR119ACACBACACANPC1RAB9A | |
| SCHEMBL1841648 | 0.84 | ACACB (0.46) | GPR119ACACBACACAPPARGPPARD | |
| SCHEMBL2389594 | 0.84 | PPARG (0.39) | GPR119PPARGPPARDMAOABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011128394-A1 | 3-SUBSTITUTED 5-(PYRROLIDINE-1-CARBONYL) PYRROLIDINE AND ITS DERIVATIVES FOR USE IN THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011128394-A1 | 3-SUBSTITUTED 5-(PYRROLIDINE-1-CARBONYL) PYRROLIDINE AND ITS DERIVATIVES FOR USE IN THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2011-10-20 | — | — | WO | disclosed |