Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.62 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604201 | 0.93 | DDB1 (0.54) | DDB1CRBNESR2MAPK1NR1H2 | |
| SCHEMBL25604267 | 0.93 | DDB1 (0.56) | DDB1CRBNESR2MAPK1NR1H2 | |
| SCHEMBL25604357 | 0.89 | DDB1 (0.52) | DDB1CRBNESR2NR1H2 | |
| SCHEMBL25825842 | 0.86 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL25604143 | 0.83 | DDB1 (0.62) | DDB1CRBNESR2NR1H2BRD4 | |
| SCHEMBL25598019 | 0.81 | CRBN (0.45) | DDB1CRBN | |
| SCHEMBL31443980 | 0.80 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL31443625 | 0.79 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL31323505 | 0.79 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL25817820 | 0.77 | CRBN (0.43) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |