SCHEMBL25825842

SCHEMBL25825842

CC(C)(C)OC(=O)N1CC2(Cc3ccc4c(C5CCC(=O)NC5=O)noc4c3C2)C1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 17/20 0.49
CRBN Q96SW2 17/20 0.49
SCD5 Q86SK9 1/20 0.33
GPR119 Q8TDV5 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25825904 0.86 DDB1 (0.62) DDB1CRBN
SCHEMBL25604357 0.85 DDB1 (0.52) DDB1CRBNGPR119
SCHEMBL25604267 0.85 DDB1 (0.56) DDB1CRBN
SCHEMBL25604201 0.85 DDB1 (0.54) DDB1CRBN
SCHEMBL25817837 0.84 DDB1 (0.44) DDB1CRBN
SCHEMBL25601335 0.80 DDB1 (0.41) DDB1CRBN
SCHEMBL31443980 0.79 DDB1 (0.52) DDB1CRBNGPR119
SCHEMBL31443625 0.78 DDB1 (0.51) DDB1CRBNGPR119
SCHEMBL31323505 0.78 DDB1 (0.54) DDB1CRBNGPR119
SCHEMBL31323705 0.76 DDB1 (0.47) DDB1CRBNSCD5GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125944-A1 COMPOUND CONTAINING HETEROCYCLIC RING 正大天晴药业集团股份有限公司 2023-07-06 WO disclosed