Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913813 | 0.85 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL20796131 | 0.84 | MEN1 (0.74) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL8327369 | 0.84 | MEN1 (0.69) | MEN1KMT2AMAPTLMNAALOX12 | |
| Methane SCHEMBL27598399 | 0.84 | MEN1 (0.97) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL5800553 | 0.83 | MEN1 (0.73) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL912778 | 0.83 | MEN1 (1.00) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL10709186 | 0.83 | MEN1 (0.73) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL6803769 | 0.83 | MEN1 (0.73) | MEN1KMT2AMAPTLMNAALOX12 | |
| SCHEMBL3178389 | 0.79 | MAPT (0.71) | MEN1KMT2AMAPTALOX12RAB9A | |
| SCHEMBL11711180 | 0.79 | RAB9A (1.00) | MEN1KMT2AMAPTLMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MEN1 1948/4885KMT2A 3974/4885MAPT 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.