Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999503 | 0.84 | GAK (0.58) | MAPK1CCNCCDK8MAPKAPK2PDGFRA | |
| SCHEMBL25825376 | 0.82 | KMT2A (0.68) | MAPTKMT2AUSP2ALDH1A1KDM4E | |
| SCHEMBL30180507 | 0.82 | KMT2A (0.80) | MAPTKMT2AUSP2ALDH1A1KDM4E | |
| SCHEMBL19151510 | 0.82 | KMT2A (0.80) | MAPTKMT2AUSP2ALDH1A1KDM4E | |
| SCHEMBL23999839 | 0.82 | MAPK1 (0.46) | MAPTKMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL23999859 | 0.81 | MAPK1 (0.47) | MAPTALDH1A1MAPK1TDP1MAPKAPK2 | |
| SCHEMBL23999492 | 0.80 | GAK (0.59) | CCNCCDK8MAPKAPK2PDGFRAGAK | |
| SCHEMBL17675214 | 0.80 | PDGFRA (0.55) | MAPTALDH1A1PDGFRAKDRHTT | |
| SCHEMBL28783174 | 0.79 | MAPT (0.70) | MAPTKMT2AUSP2ALDH1A1KDM4E | |
| SCHEMBL25826242 | 0.79 | MAPT (0.54) | MAPTKMT2AUSP2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAPT 3999/4885KMT2A 3974/4885USP2 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.