SCHEMBL25826256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23999793	0.88	HCAR3 (0.50)	HCAR3MAPKAPK2KDM4ERETKMT2A
	SCHEMBL23999501	0.86	HCAR3 (0.48)	HCAR3MAPKAPK2KDM4EHTTRET
	SCHEMBL23999540	0.85	HCAR3 (0.47)	HCAR3MAPKAPK2KDM4ERETMAPT
	SCHEMBL23999974	0.82	GAK (0.48)	HCAR3MAPKAPK2CDK8CLK4SLC22A12
	SCHEMBL25826240	0.81	KMT2A (0.57)	HCAR3MAPKAPK2LMNAKDM4EPOLB
	SCHEMBL23999854	0.80	IP6K1 (0.43)	HCAR3MAPKAPK2HPGDKDM4ECDK8
	SCHEMBL23999537	0.80	MAPKAPK2 (0.43)	HCAR3MAPKAPK2HPGDCDK8ACVR1
	SCHEMBL23999930	0.79	KMT2A (0.51)	MAPKAPK2HPGDLMNAKDM4EPOLB
	SCHEMBL23999939	0.79	IP6K1 (0.45)	HCAR3MAPKAPK2HPGDCDK8ACVR1
	SCHEMBL23999979	0.78	MAPKAPK2 (0.42)	HCAR3MAPKAPK2RETSLC22A12HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.