Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | UGCG | Q16739 | 2/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4162511 | 1.00 | L3MBTL1 (0.63) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL18898775 | 1.00 | L3MBTL1 (0.63) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL15923313 | 1.00 | L3MBTL1 (0.63) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL12561325 | 0.98 | L3MBTL1 (0.60) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL21215156 | 0.94 | L3MBTL1 (0.57) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL16845882 | 0.94 | TSHR (0.56) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL13909725 | 0.90 | L3MBTL1 (0.57) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL9011646 | 0.89 | TSHR (0.67) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL9011624 | 0.89 | TSHR (0.67) | L3MBTL1TDP1TSHRMEN1KMT2A | |
| SCHEMBL9011734 | 0.89 | TSHR (0.67) | L3MBTL1TDP1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |