Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30360070 | 0.90 | ABCB1 (0.35) | ABCB1PLA2G4A | |
| SCHEMBL15865693 | 0.88 | ABCB1 (0.35) | ABCB1CYP1A2CYP2C19MEN1NPC1 | |
| SCHEMBL25826886 | 0.87 | ABCB1 (0.36) | ABCB1PLA2G4ACYP1A2CYP2C19NPC1 | |
| SCHEMBL27124306 | 0.86 | ABCB1 (0.37) | ABCB1PLA2G4ACYP1A2CYP2C19MEN1 | |
| SCHEMBL14023845 | 0.86 | ABCB1 (0.37) | ABCB1CYP1A2CYP2C19MEN1NPC1 | |
| SCHEMBL15478873 | 0.86 | ABCB1 (0.37) | ABCB1CYP1A2CYP2C19MEN1NPC1 | |
| SCHEMBL14023067 | 0.86 | ABCB1 (0.37) | ABCB1CYP1A2CYP2C19MEN1NPC1 | |
| SCHEMBL25827016 | 0.85 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL30716467 | 0.85 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL25827793 | 0.83 | ABCB1 (0.38) | ABCB1PLA2G4ACYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129518-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |