Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25836077 | 0.90 | ABCB1 (0.39) | ABCB1PLA2G4ARAB9ANPC1MAPT | |
| SCHEMBL25825751 | 0.89 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL27124306 | 0.86 | ABCB1 (0.37) | ABCB1PLA2G4ARAB9ANPC1MAPT | |
| SCHEMBL30360082 | 0.85 | ABCB1 (0.47) | ABCB1PLA2G4ARAB9ANPC1MAPT | |
| SCHEMBL25832393 | 0.83 | ABCB1 (0.37) | ABCB1PLA2G4ARAB9ANPC1MAPT | |
| SCHEMBL25826798 | 0.83 | ABCB1 (0.34) | ABCB1PLA2G4ARAB9ANPC1MAPT | |
| SCHEMBL25829813 | 0.83 | PLA2G4A (0.36) | PLA2G4A | |
| SCHEMBL25828331 | 0.81 | — | — | |
| SCHEMBL25828774 | 0.80 | ABCB1 (0.34) | ABCB1PLA2G4ARAB9ANPC1MAPT | |
| SCHEMBL18542798 | 0.80 | PTPRB (0.30) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129518-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |