Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31251101 | 0.88 | KDM4E (0.54) | ALDH1A1KDM4EMAPTCA1CA2 | |
| SCHEMBL14108189 | 0.86 | PLK1 (0.49) | ALDH1A1KDM4EMAPTHSD17B10HPGD | |
| SCHEMBL821898 | 0.85 | KDM4E (0.59) | ALDH1A1KDM4EMAPTCA1CA2 | |
| SCHEMBL20876268 | 0.83 | CA12 (0.62) | ALDH1A1KDM4EMAPTCA1CA2 | |
| SCHEMBL15543469 | 0.82 | TDP1 (0.52) | ALDH1A1KDM4EMAPTCA1CA2 | |
| SCHEMBL31084748 | 0.82 | NOTUM (0.53) | ALDH1A1KDM4EMAPTCA1CA2 | |
| SCHEMBL2944059 | 0.82 | NOTUM (0.53) | ALDH1A1KDM4EMAPTCA1CA2 | |
| SCHEMBL14683914 | 0.82 | HDAC8 (0.51) | ALDH1A1MAPTHPGDSMN1; SMN2MEN1 | |
| SCHEMBL10420348 | 0.80 | CA1 (0.59) | ALDH1A1KDM4EMAPTCA1CA2 | |
| SCHEMBL13634519 | 0.80 | HPGD (0.51) | ALDH1A1MAPTHPGDMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880666-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-06-28 | — | — | EP | disclosed |