Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15543469 | 0.89 | TDP1 (0.52) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL31084748 | 0.89 | NOTUM (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL1170268 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL2944059 | 0.89 | NOTUM (0.53) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL2054476 | 0.89 | HDAC8 (0.51) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL27679219 | 0.88 | NOTUM (0.49) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL3990255 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL15701587 | 0.86 | NOTUM (0.48) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL45823 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL14108189 | 0.85 | PLK1 (0.49) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159347-B | Preparation method of picolitamide | 常州工程职业技术学院 | 2022-06-07 | — | — | CN | claimed |
| CN-112159347-A | Preparation method of picolitamide | 常州工程职业技术学院 | 2021-01-01 | — | — | CN | claimed |
| US-12595251-B2 | Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| EP-4603484-A2 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | Georgia State University Research Foundation, Inc. (US) | 2025-08-20 | — | — | EP | disclosed |
| EP-4323350-A1 | ISOINDOLINONE COMPOUNDS | Monte Rosa Therapeutics AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| US-20240051936-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS AG (CH) | 2024-02-15 | — | — | US | disclosed |
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20230105108-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-04-06 | — | — | US | disclosed |
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2023-01-19 | — | — | US | disclosed |
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2023-01-19 | — | — | US | disclosed |
| EP-1809613-A2 | METHODS OF MAKING 2,6-DIARYL PIPERIDINE DERIVATIVES | ANORMED INC. (CA) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006049764-A2 | METHODS OF MAKING 2,6-DIARYL PIPERIDINE DERIVATIVES | ANORMED INC. (CA) | 2006-05-11 | — | — | WO | disclosed |
| EP-1615633-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY | ANORMED INC. (CA) | 2006-01-18 | — | — | EP | disclosed |
| US-20050154201-A1 | Methods of making 2,6-diaryl piperidine derivatives | ANORMED CORPORATION (CA) | 2005-07-14 | — | — | US | disclosed |
| US-20050059702-A1 | Chemokine receptor binding heterocyclic compounds with enhanced efficacy | ANORMED CORPORATION (CA) | 2005-03-17 | — | — | US | disclosed |
| WO-2004093817-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY | ANORMED INC. (CA) | 2004-11-04 | — | — | WO | disclosed |
| US-5191121-A | Sunscreen | KAO CORPORATION (JP) | 1993-03-02 | — | — | US | disclosed |
| US-5146002-A | Sunscreen | KAO CORPORATION (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0416564-A2 | Novel aroyl ketone derivative, UV ray absorber comprising the same, and cosmetic composition containing the same | KAO CORPORATION (JP) | 1991-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | MAPK1, MAPK8, MAPK7 | KDM4E 4410/4885ALDH1A1 3835/4885MAPT 880/4885 |
| US-20050154201-A1 | Methods of making 2,6-diaryl piperidine derivatives | ALDH7A1, DPYD, ALDH1A1 | KDM4E 1536/4885ALDH1A1 3/4885MAPT 3937/4885 |
| US-20230105108-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | BPGM, MYD88, PGLS | KDM4E 4614/4885ALDH1A1 4445/4885MAPT 3202/4885 |
| US-12595251-B2 | Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics | CLIC1, CBR3, CBR1 | KDM4E 4720/4885ALDH1A1 3581/4885MAPT 4877/4885 |
| US-20240051936-A1 | ISOINDOLINONE COMPOUNDS | CRBN, CDR2, POU2F2 | KDM4E 2644/4885ALDH1A1 1907/4885MAPT 4743/4885 |
| US-20050059702-A1 | Chemokine receptor binding heterocyclic compounds with enhanced efficacy | CXCR4, CXCR1, CCR5 | KDM4E 3731/4885ALDH1A1 290/4885MAPT 4466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.