Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21105840 | 0.88 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL21107577 | 0.83 | KDM4E (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21501413 | 0.83 | KDM4E (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL15160763 | 0.83 | KDM4E (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21106771 | 0.83 | KDM4E (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL23787476 | 0.80 | KDM4E (0.37) | MEN1KMT2A | |
| SCHEMBL15160765 | 0.80 | KDM4E (0.37) | MEN1KMT2AALDH1A1 | |
| SCHEMBL22861730 | 0.78 | TSHR (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL26482397 | 0.78 | KDM4E (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL22965639 | 0.77 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | MEN1 4055/4885KMT2A 445/4885ALDH1A1 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.