Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IARS1 | P41252 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826934 | 1.00 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL25827282 | 1.00 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL7396618 | 0.87 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL7358388 | 0.86 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19GAA | |
| Hydrochloric Acid SCHEMBL7396617 | 0.86 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL7140073 | 0.83 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL10448209 | 0.80 | ECE1 (0.50) | TERTUSP2TSHRDPP4DPP8 | |
| SCHEMBL10448521 | 0.80 | MEN1 (0.49) | L3MBTL1KMT2ACTSLCTSB | |
| SCHEMBL10085314 | 0.80 | GAA (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19GAA | |
| SCHEMBL5494763 | 0.78 | ANPEP (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |