Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396618 | 0.89 | CYP1A2 (0.42) | CYP1A2GAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL7396617 | 0.87 | CYP1A2 (0.41) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL25827282 | 0.86 | CYP1A2 (0.40) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL25826934 | 0.86 | CYP1A2 (0.40) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL25827289 | 0.86 | CYP1A2 (0.40) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL7140073 | 0.85 | CYP1A2 (0.44) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL10085314 | 0.81 | GAA (0.46) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL5494763 | 0.79 | ANPEP (0.41) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL5494766 | 0.79 | ANPEP (0.41) | CYP1A2GAAMGAMSIMGAM2 | |
| SCHEMBL27880698 | 0.76 | GAA (0.45) | CYP1A2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242494-B1 | ANGIOGENESIS INHIBITORS, ANTITUMOR AGENTS, DIABETIC RETINOPATHY, AND ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES | 2001-06-05 | — | — | US | claimed |