SCHEMBL25827327

SCHEMBL25827327

CSC1O[C@H]([C@H](NC(=O)C(F)(F)F)[C@H](C)S)C(O)[C@@H](O)[C@H]1O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.41
LMNA P02545 1/20 0.41
CYP2C9 P11712 1/20 0.41
HTR2A P28223 1/20 0.39
ADRA1A P35348 1/20 0.39
ALDH1A1 P00352 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTR2C P28335 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24047298 1.00 ALB (0.41) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL25831639 1.00 ALB (0.41) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL24047242 1.00 ALB (0.41) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL26332859 0.88 ALB (0.51) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL20729602 0.88 ALB (0.51) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL24299247 0.88 ALB (0.51) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL14194247 0.88 ALB (0.51) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL24047299 0.76 ALB (0.35) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL24047292 0.76 ALB (0.35) ALBLMNACYP2C9HTR2AADRA1A
SCHEMBL25827337 0.76 ALB (0.35) ALBLMNACYP2C9HTR2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203081-A1 LINCOSAMIDE ANTIBIOTICS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203081-A1 LINCOSAMIDE ANTIBIOTICS AND USES THEREOF NPEPPS, TLR7, ASNS ALB 1451/4885LMNA 218/4885CYP2C9 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.