Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18520796 | 0.89 | LMNA (0.50) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL25826354 | 0.82 | LMNA (0.42) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL12322931 | 0.80 | LMNA (0.43) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL31326706 | 0.78 | LMNA (0.69) | LMNAEPHX2MAPTNAPEPLDCASP2 | |
| SCHEMBL8851730 | 0.77 | LMNA (0.57) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL5811678 | 0.77 | LMNA (0.47) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL13239300 | 0.77 | LMNA (0.41) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL15145437 | 0.76 | HTT (0.40) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL21916370 | 0.76 | LMNA (0.60) | LMNAALDH1A1EPHX2HTTMAPT | |
| SCHEMBL4093907 | 0.75 | LMNA (0.42) | LMNAALDH1A1EPHX2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |