Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21326064 | 0.87 | PARP1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21751143 | 0.87 | PARP1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31114244 | 0.85 | HTR2C (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14209521 | 0.85 | HTR2C (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL25344606 | 0.81 | SMN1; SMN2 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL636520 | 0.81 | SMN1; SMN2 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4847560 | 0.81 | SMN1; SMN2 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8863381 | 0.81 | NPSR1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8293214 | 0.81 | NPSR1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL18220637 | 0.81 | HTR2C (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203081-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203081-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | NPEPPS, TLR7, ASNS | PSEN1 2782/4885PSEN2 1891/4885APH1B 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.