Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350668 | 0.98 | ALDH1A1 (0.44) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM | |
| SCHEMBL11428167 | 0.82 | GSK3A (0.44) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM | |
| SCHEMBL16004440 | 0.73 | GSK3A (0.50) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM | |
| SCHEMBL4763682 | 0.73 | ALDH1A1 (0.49) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM | |
| SCHEMBL9351790 | 0.73 | ALDH1A1 (0.38) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM | |
| SCHEMBL9350770 | 0.72 | ALDH1A1 (0.42) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM | |
| SCHEMBL11847806 | 0.71 | GSK3A (0.54) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM | |
| SCHEMBL1419240 | 0.71 | HSD17B10 (0.36) | ALDH1A1SMN1; SMN2POLBHSD17B10RAB9A | |
| SCHEMBL1419576 | 0.71 | GSK3A (0.36) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2HTT | |
| SCHEMBL11840108 | 0.69 | JAK2 (0.47) | ALDH1A1CYP2C9CYP2C19SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |