Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | CPA2 | P48052 | 1/20 | 0.46 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865877 | 0.85 | CTSS (0.60) | ACELMNACTSSCTSKPAM | |
| SCHEMBL20079849 | 0.85 | CTSS (0.60) | ACELMNACTSSCTSKPAM | |
| SCHEMBL12313515 | 0.85 | ESR1 (0.54) | GRIA1FOLH1ACECPA1MME | |
| SCHEMBL5490272 | 0.85 | ESR1 (0.54) | GRIA1FOLH1ACECPA1MME | |
| SCHEMBL26778812 | 0.85 | ESR1 (0.54) | GRIA1FOLH1ACECPA1MME | |
| SCHEMBL16509238 | 0.83 | FOLH1 (0.47) | GRIA1FOLH1ACECPA1MME | |
| Acetyl Tyrosine SCHEMBL1204300 | 0.83 | FOLH1 (0.66) | GRIA1FOLH1ACECPA1MME | |
| Acetyl Tyrosine SCHEMBL8977601 | 0.83 | FOLH1 (0.66) | GRIA1FOLH1ACECPA1MME | |
| Acetyl Tyrosine SCHEMBL313539 | 0.83 | FOLH1 (0.66) | GRIA1FOLH1ACECPA1MME | |
| Acetyl Tyrosine SCHEMBL8977600 | 0.83 | FOLH1 (0.66) | GRIA1FOLH1ACECPA1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227508-A1 | SPLIT INTEIN-BASED SELECTION FOR PEPTIDE BINDERS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-07-20 | — | — | US | disclosed |
| US-9149541-B2 | Tyrosine ligation process | NOVARTIS AG (CH) | 2015-10-06 | — | — | US | disclosed |
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | SCRIPPS RESEARCH INST (US) | 2014-12-25 | — | — | US | disclosed |
| US-8765920-B2 | Tyrosine bioconjugation through aqueous Ene-like reactions | THE SCRIPPS RESEARCH INSTITUTE (US) | 2014-07-01 | — | — | US | disclosed |
| US-20140141034-A1 | TYROSINE LIGATION PROCESS | NOVARTIS AG (CH) | 2014-05-22 | — | — | US | disclosed |
| US-20120289682-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | THE SCRIPPS RESEARCH INSTITUTE | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227508-A1 | SPLIT INTEIN-BASED SELECTION FOR PEPTIDE BINDERS | FURIN, SARS1, BST2 | GRIA1 4334/4885FOLH1 919/4885ACE 72/4885 |
| US-20140141034-A1 | TYROSINE LIGATION PROCESS | ACP1, LTK, TTL | GRIA1 948/4885FOLH1 1882/4885ACE 1141/4885 |
| US-20140378668-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | TYR, DNPEP, TH | GRIA1 1829/4885FOLH1 1414/4885ACE 270/4885 |
| US-20120289682-A1 | Tyrosine Bioconjugation through Aqueous Ene-Like Reactions | TYR, DNPEP, TH | GRIA1 1829/4885FOLH1 1414/4885ACE 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.