Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 20/20 | 0.43 |
| ▸ | PLK1 | P53350 | 2/20 | 0.36 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21349331 | 0.89 | WEE1 (0.52) | WEE1PLK1 | |
| SCHEMBL21349629 | 0.77 | WEE1 (0.64) | WEE1PLK1 | |
| SCHEMBL23126643 | 0.76 | WEE1 (0.40) | WEE1PLK1 | |
| SCHEMBL20875616 | 0.75 | WEE1 (0.58) | WEE1PLK1PKMYT1 | |
| SCHEMBL24740820 | 0.74 | WEE1 (0.62) | WEE1 | |
| SCHEMBL22851870 | 0.74 | WEE1 (0.58) | WEE1PLK1 | |
| SCHEMBL25676277 | 0.70 | WEE1 (0.51) | WEE1PLK1 | |
| SCHEMBL25818940 | 0.69 | WEE1 (0.67) | WEE1PLK1 | |
| SCHEMBL21350111 | 0.67 | WEE1 (0.64) | WEE1PLK1 | |
| SCHEMBL25576991 | 0.67 | WEE1 (0.64) | WEE1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |