SCHEMBL25828268

SCHEMBL25828268

O=c1c2c(ccc3c4ccccc4n(-c4ccc5ccccc5c4)c32)c2ccc3c4ccccc4n(-c4ccc5ccccc5c4)c3c2n1-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 2/20 0.40
ALDH1A1 P00352 4/20 0.40
POLB P06746 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.40
BRCA1 P38398 1/20 0.40
HSD17B10 Q99714 1/20 0.40
RAB9A P51151 2/20 0.39
PMM2 O15305 1/20 0.39
MPI P34949 1/20 0.39
PHOSPHO1 Q8TCT1 1/20 0.39
NPC1 O15118 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK8 P45983 2/20 0.39
MAPK9 P45984 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828269 0.88 L3MBTL1 (0.45) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25828271 0.88 L3MBTL1 (0.45) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25829018 0.88 KDM4E (0.41) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL17189460 0.88 KDM4E (0.53) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25828177 0.88 KDM4E (0.53) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL15073715 0.87 KDM4E (0.49) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL15073675 0.85 KDM4E (0.53) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25828261 0.84 KDM4E (0.46) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL25828264 0.84 KDM4E (0.46) KDM4EATML3MBTL1HPGDALDH1A1
SCHEMBL19769511 0.84 KDM4E (0.53) KDM4EATML3MBTL1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed