SCHEMBL25828769

SCHEMBL25828769

C=CCOC(=O)NCC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.50
▸ TLR2 O60603 2/20 0.47
▸ MDM2 Q00987 5/20 0.46
▸ TGM2 P21980 4/20 0.46
▸ MDM4 O15151 1/20 0.45
▸ TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401249 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL178701 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL21462054 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL29958970 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL178771 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL25358347 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL29400961 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL29391986 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL29350360 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4
SCHEMBL4600836 0.94 KMT2A (0.57) KMT2ATLR2MDM2TGM2MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR PHARMACEUTICALS CO., LTD. (JP) 2023-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE TFRC, SLC3A2, SLC7A1 KMT2A 2608/4885TLR2 1465/4885MDM2 4069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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