Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206550 | 0.81 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL26859096 | 0.77 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL5121295 | 0.72 | HCAR2 (0.40) | HCAR2 | |
| SCHEMBL21389734 | 0.70 | HCAR2 (0.39) | HCAR2 | |
| SCHEMBL21209899 | 0.69 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL13886980 | 0.69 | HCAR2 (0.42) | HCAR2 | |
| SCHEMBL12058917 | 0.66 | HCAR2 (0.39) | HCAR2 | |
| SCHEMBL21610733 | 0.66 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL26858880 | 0.66 | HCAR2 (0.35) | HCAR2 | |
| SCHEMBL10889352 | 0.66 | HCAR2 (0.35) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219942-A1 | COMPOUNDS COMPRISING A THREE RING CORE AS PD-1/PD-L1 BLOCKERS | RELIVE THERAPEUTICS INC. (CA) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219942-A1 | COMPOUNDS COMPRISING A THREE RING CORE AS PD-1/PD-L1 BLOCKERS | CD274, PDCD1, PDCD1LG2 | HCAR2 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.