SCHEMBL25829320 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	WEE1	P30291	19/20	0.47

▸	EGFR	P00533	1/20	0.44

▸	CYP3A4	P08684	1/20	0.44

▸	PLK1	P53350	1/20	0.44

▸	MAP3K19	Q56UN5	1/20	0.44

▸	PLK3	Q9H4B4	1/20	0.44

▸	PLK2	Q9NYY3	1/20	0.44

▸	FGFR1	P11362	1/20	0.33

▸	CDK4	P11802	1/20	0.33

▸	CCNA2	P20248	1/20	0.33

▸	FGFR2	P21802	1/20	0.33

▸	FGFR4	P22455	1/20	0.33

▸	FGFR3	P22607	1/20	0.33

▸	CCND1	P24385	1/20	0.33

▸	CDK2	P24941	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25831722	0.84	WEE1 (0.40)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25831457	0.82	WEE1 (0.43)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25829207	0.81	WEE1 (0.59)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25828130	0.80	WEE1 (0.72)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25826957	0.79	WEE1 (0.77)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25830690	0.79	WEE1 (0.77)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25831084	0.77	WEE1 (0.51)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25829318	0.75	WEE1 (0.55)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25831534	0.75	WEE1 (0.48)	WEE1EGFRCYP3A4PLK1MAP3K19
SCHEMBL25831326	0.69	WEE1 (0.48)	WEE1EGFRCYP3A4PLK1MAP3K19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023125944-A1	COMPOUND CONTAINING HETEROCYCLIC RING	正大天晴药业集团股份有限公司	2023-07-06	—	—	WO	disclosed