Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 11/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.31 |
| ▸ | CCND1 | P24385 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | CCND2 | P30279 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25831457 | 0.85 | WEE1 (0.43) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25829320 | 0.84 | WEE1 (0.47) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25831534 | 0.80 | WEE1 (0.48) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25831084 | 0.78 | WEE1 (0.51) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25831732 | 0.75 | WEE1 (0.44) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25829207 | 0.74 | WEE1 (0.59) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25828130 | 0.73 | WEE1 (0.72) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25830690 | 0.72 | WEE1 (0.77) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25826957 | 0.72 | WEE1 (0.77) | WEE1EGFRCYP3A4PLK1MAP3K19 | |
| SCHEMBL25831326 | 0.71 | WEE1 (0.48) | WEE1EGFRCYP3A4PLK1MAP3K19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |