SCHEMBL25829665

SCHEMBL25829665

COC(=O)c1ccc(-c2c3cc(F)c(=O)cc-3oc3cc(O)c(F)cc23)c(C)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.60
MEN1 O00255 7/20 0.42
KMT2A Q03164 7/20 0.42
POLB P06746 6/20 0.42
MAPT P10636 6/20 0.42
USP2 O75604 6/20 0.42
L3MBTL1 Q9Y468 5/20 0.42
HPGD P15428 5/20 0.42
GAA P10253 5/20 0.42
KDM4E B2RXH2 5/20 0.42
RECQL P46063 5/20 0.42
TDP1 Q9NUW8 5/20 0.42
MAPK1 P28482 4/20 0.42
ALDH1A1 P00352 4/20 0.42
THRB P10828 4/20 0.42
HTT P42858 3/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CASP6 P55212 2/20 0.42
ABL1 P00519 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19676682 0.89 FTO (0.63) FTOMEN1KMT2APOLBMAPT
SCHEMBL22139485 0.89 FTO (0.69) FTOMEN1KMT2APOLBMAPT
SCHEMBL25829599 0.87 FTO (0.59) FTOMEN1KMT2APOLBMAPT
SCHEMBL18650245 0.84 FTO (0.65) FTOMEN1KMT2APOLBMAPT
SCHEMBL18827155 0.83 FTO (0.55) FTOMEN1KMT2APOLBMAPT
SCHEMBL18653024 0.81 FTO (0.72) FTOMEN1KMT2APOLBMAPT
SCHEMBL22128453 0.81 FTO (0.60) FTOMEN1KMT2APOLBMAPT
SCHEMBL22139497 0.81 FTO (0.60) FTOMEN1KMT2APOLBMAPT
SCHEMBL21945700 0.81 FTO (0.60) FTOMEN1KMT2APOLBMAPT
SCHEMBL22139508 0.81 FTO (0.60) FTOMEN1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132337-A1 FLUORESCENT STAINING METHOD 国立大学法人大阪大学 2023-07-13 WO disclosed