Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26192914 | 0.88 | SMN1; SMN2 (0.38) | RAB9AALDH1A1NPC1MEN1LMNA | |
| SCHEMBL25838665 | 0.82 | SCN4A (0.54) | HDAC1HDAC2PARP1RAB9AALDH1A1 | |
| SCHEMBL30510067 | 0.81 | MEN1 (0.46) | ALDH1A1MEN1KMT2ATGFBR1KDM4E | |
| SCHEMBL25255928 | 0.81 | MEN1 (0.46) | ALDH1A1MEN1KMT2ATGFBR1KDM4E | |
| SCHEMBL25378723 | 0.79 | TDP1 (0.36) | PARP1RAB9AALDH1A1SCN4ANPC1 | |
| SCHEMBL25379506 | 0.75 | HDAC1 (0.40) | HDAC1HDAC2RAB9AALDH1A1ALOX5 | |
| SCHEMBL25380341 | 0.71 | JAK2 (0.35) | PARP1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL25379856 | 0.71 | PSD (0.39) | ALDH1A1SCN4ASMN1; SMN2TGFBR1KDM4E | |
| SCHEMBL30510053 | 0.69 | KDM4E (0.50) | ALDH1A1TGFBR1KDM4E | |
| SCHEMBL25375677 | 0.69 | KDM4E (0.50) | ALDH1A1TGFBR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |