SCHEMBL25838665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25256189	0.82	SCN4A (0.54)	SCN4AKEAP1KMT2ARAB9AMAPK14
	SCHEMBL25378325	0.82	SCN4A (0.50)	SCN4AKEAP1KMT2ARAB9AMAPK14
	SCHEMBL25830430	0.82	HDAC1 (0.38)	SCN4AKMT2AHDAC1HDAC2RAB9A
	SCHEMBL25832619	0.80	SCN4A (0.51)	SCN4AKEAP1KMT2ARAB9ANPC1
	SCHEMBL30510152	0.79	SCN4A (0.50)	SCN4AKEAP1KMT2AMEN1ALDH1A1
	SCHEMBL25302752	0.79	SCN4A (0.50)	SCN4AKEAP1KMT2AMEN1ALDH1A1
	SCHEMBL989300	0.79	SCN4A (0.79)	SCN4AKEAP1KMT2ARAB9AMAPK14
	SCHEMBL26193412	0.77	SCN4A (0.48)	SCN4AKEAP1KMT2AMAPK14MEN1
	SCHEMBL6261817	0.76	KEAP1 (0.58)	SCN4AKEAP1KMT2ARAB9ANPC1
	SCHEMBL30510147	0.75	SCN4A (0.59)	SCN4AKEAP1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.