Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | NOS2 | P35228 | 5/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258218 | 0.98 | KMT2A (0.45) | CA1CA2CA4KMT2ANOS1 | |
| SCHEMBL258092 | 0.93 | — | — | |
| SCHEMBL911022 | 0.83 | — | — | |
| SCHEMBL258289 | 0.81 | — | — | |
| SCHEMBL6564603 | 0.80 | CA1 (0.41) | CA1CA2CA4KMT2A | |
| SCHEMBL905660 | 0.79 | KMT2A (0.48) | CA1CA2CA4KMT2ANOS1 | |
| SCHEMBL258236 | 0.79 | KMT2A (0.48) | CA1CA2CA4KMT2ANOS1 | |
| SCHEMBL3291610 | 0.78 | CA1 (0.48) | CA1CA2CA4KMT2ANOS1 | |
| SCHEMBL2339292 | 0.77 | KMT2A (0.42) | CA1CA2CA4KMT2ANOS1 | |
| SCHEMBL487148 | 0.74 | NOS1 (0.39) | CA1CA2CA4NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334683-B1 | SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS | MSD ITALIA SRL (IT) | 2017-03-22 | — | — | EP | disclosed |
| US-8470823-B2 | Saturated bicyclic heterocyclic derivatives as SMO antagonists | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.R.L. (IT) | 2013-06-25 | — | — | US | disclosed |
| EP-2423297-B1 | Hydraulic oil composition | NIPPON OIL CORP (JP) | 2013-06-05 | — | — | EP | disclosed |
| EP-1721957-B1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT | NIPPON OIL CORP (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-8299006-B2 | Compressor oil composition | NIPPON OIL CORPORATION (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8247360-B2 | Heat treating oil composition | NIPPON OIL CORPORATION (JP) | 2012-08-21 | — | — | US | disclosed |
| US-8240235-B2 | Method of minimal quantity lubrication cutting/grinding processing and oil composition used therefor | NIPPON OIL CORPORATION (JP) | 2012-08-14 | — | — | US | disclosed |
| US-8236740-B2 | Lubricating oil composition | NIPPON OIL CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-8232233-B2 | Lubricating oil composition for machine tools | NIPPON OIL CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8227387-B2 | Metalworking oil composition | NIPPON OIL CORPORATION (JP) | 2012-07-24 | — | — | US | disclosed |
| EP-1702972-A1 | METALWORKING FLUID | Nippon Oil Corporation (JP) | 2006-09-20 | — | — | EP | disclosed |
| US-20060111256-A1 | Having a diurea thickener with at least one aromatic or aliphatic ring, paraffin oxides phosphite or phosphate compounds, a organic molybdenum compound and a lithium soap added to the base oil; improved friction resistance at high temperatures | NIPPPON OIL CORPORATION (JP) | 2006-05-25 | — | — | US | disclosed |
| US-20060052257-A1 | Grease composition | NIPPON OIL CORPORATION (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1314774-B1 | Grease composition | NIPPON OIL CORP (JP) | 2005-08-03 | — | — | EP | disclosed |
| EP-1559771-A1 | GREASE COMPOSITION | Nippon Oil Corporation (JP) | 2005-08-03 | — | — | EP | disclosed |
| EP-1500693-A1 | GREASE COMPOSITION | Nippon Oil Corporation (JP) | 2005-01-26 | — | — | EP | disclosed |
| US-20040116309-A1 | Oil composition for cutting and grinding by minimal quantity lubrication system | NIPPON OIL CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20040116308-A1 | Oil for cutting and grinding by ultra low volume oil feed system and for sliding surface and method for cutting and grinding by ultra low volume feed system using the oil | NIPPON OIL CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-20030139302-A1 | Grease composition | NIPPON OIL CORPORATION | 2003-07-24 | — | — | US | disclosed |
| EP-1314774-A1 | Grease composition | Nippon Oil Corporation (JP) | 2003-05-28 | — | — | EP | disclosed |