SCHEMBL25830503

SCHEMBL25830503

O=c1c2cc3[nH]c4ccccc4c3cc2c2cc3c(cc2n1-c1ccccc1)c1ccccc1n3-c1ccc2c(c1)oc1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 1/20 0.37
PDE7B Q9NP56 1/20 0.37
CYP1A2 P05177 1/20 0.37
ALDH1A1 P00352 7/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
BRCA1 P38398 1/20 0.37
RXFP1 Q9HBX9 4/20 0.36
PPARG P37231 3/20 0.36
NR2E3 Q9Y5X4 3/20 0.36
NCOR2 Q9Y618 3/20 0.36
HTT P42858 2/20 0.35
KDM4E B2RXH2 5/20 0.35
GAA P10253 1/20 0.35
PTGER4 P35408 1/20 0.35
AHR P35869 1/20 0.35
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25829632 0.89 ALDH1A1 (0.43) CYP1A2ALDH1A1KMT2AHSD17B10MEN1
SCHEMBL25829308 0.87 PDE7A (0.42) PDE7APDE7BCYP1A2ALDH1A1KMT2A
SCHEMBL25829630 0.82 ALDH1A1 (0.43) CYP1A2ALDH1A1KMT2AHSD17B10MEN1
SCHEMBL25679720 0.82 KDM4E (0.46) PDE7APDE7BCYP1A2ALDH1A1KMT2A
SCHEMBL23259732 0.81 KDM4E (0.43) CYP1A2ALDH1A1KMT2AHSD17B10MEN1
SCHEMBL23259726 0.81 KDM4E (0.45) CYP1A2ALDH1A1KMT2AHSD17B10MEN1
SCHEMBL23259727 0.81 KDM4E (0.45) CYP1A2ALDH1A1KMT2AHSD17B10MEN1
SCHEMBL22249991 0.81 AHR (0.44) CYP1A2ALDH1A1HSD17B10KDM4EAHR
SCHEMBL17228184 0.81 KDM4E (0.53) ALDH1A1KMT2AHSD17B10MEN1POLB
SCHEMBL17299939 0.80 CYP1A2 (0.44) PDE7APDE7BCYP1A2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed