SCHEMBL25830825

SCHEMBL25830825

Nc1nc(=O)n([C@@H]2CS[C@H](CO)C2)cc1F

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALB P02768 3/20 0.60
DCK P27707 15/20 0.44
POLG P54098 1/20 0.43
CACNA1F O60840 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
CACNA1D Q01668 2/20 0.37
CACNA1S Q13698 2/20 0.37
CACNA1C Q13936 2/20 0.37
PDE3A Q14432 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8088509 0.81 ALB (0.68) ALBDCKPOLGCACNA1FLMNA
SCHEMBL599406 0.80 ALB (0.56) ALBDCKPOLG
SCHEMBL599407 0.80 ALB (0.56) ALBDCKPOLG
SCHEMBL27527424 0.79 ALB (0.69) ALBDCKPOLGCACNA1FLMNA
SCHEMBL6404292 0.78 ALB (0.64) ALBDCKPOLGCACNA1FLMNA
SCHEMBL9122186 0.77 ALB (0.54) ALBDCKPOLG
SCHEMBL9067244 0.76 ALB (0.59) ALBDCKPOLGCACNA1FLMNA
SCHEMBL7124283 0.76 ALB (0.59) ALBDCKPOLGCACNA1FLMNA
SCHEMBL9067540 0.76 ALB (0.59) ALBDCKPOLGCACNA1FLMNA
Phosphoric Acid SCHEMBL599685 0.75 ALB (0.52) ALBDCKPOLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230218644-A1 COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS EWHA WOMANS UNIVERSITY (KR) 2023-07-13 US disclosed
US-20230218644-A1 COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS EWHA WOMANS UNIVERSITY (KR) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230218644-A1 COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY RESPIRATORY SYNDROME-RELATED CORONAVIRUS ACE2, ACE, TMPRSS2 ALB 1488/4885DCK 542/4885POLG 3899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.