Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 3/20 | 0.59 |
| ▸ | POLG | P54098 | 1/20 | 0.42 |
| ▸ | DCK | P27707 | 14/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067244 | 1.00 | ALB (0.59) | ALBPOLGDCKCACNA1FLMNA | |
| SCHEMBL9067540 | 1.00 | ALB (0.59) | ALBPOLGDCKCACNA1FLMNA | |
| SCHEMBL9122186 | 0.79 | ALB (0.54) | ALBPOLGDCK | |
| SCHEMBL9149293 | 0.78 | ALB (0.53) | ALBPOLGDCKLMNA | |
| SCHEMBL2036187 | 0.78 | ALB (0.53) | ALBPOLGDCKLMNA | |
| SCHEMBL9530859 | 0.77 | LMNA (0.57) | ALBPOLGCACNA1FLMNAMAPT | |
| SCHEMBL6303823 | 0.77 | ALB (0.52) | ALBPOLGDCK | |
| SCHEMBL20734859 | 0.77 | ALB (0.61) | ALBPOLGDCKCACNA1FLMNA | |
| SCHEMBL9066905 | 0.77 | ALB (0.61) | ALBPOLGDCKCACNA1FLMNA | |
| SCHEMBL5607740 | 0.77 | ALB (0.61) | ALBPOLGDCKCACNA1FLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361227-A2 | [5-carboxamide or 5-fluoro]-[2', 3'-unsaturated or 3'-modifield]-pyrimidine nucleosides | Emory University (US) | 2003-11-12 | — | — | EP | claimed |
| EP-0805683-A4 | 5-CARBOXAMIDO OR 5-FLUORO]- 2',3'-UNSATURATED OR 3'-MODIFIED]-PYRIMIDINE NUCLEOSIDES | UNIV EMORY (US) | 1999-09-01 | — | — | EP | claimed |
| EP-0805683-A1 | 5-CARBOXAMIDO OR 5-FLUORO]- 2',3'-UNSATURATED OR 3'-MODIFIED]-PYRIMIDINE NUCLEOSIDES | EMORY UNIVERSITY (US) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022778-A1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITOR | EMORY UNIVERSITY (US) | 1996-08-01 | — | — | WO | claimed |