Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861357 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL13884328 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL15160693 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL9936087 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL25110753 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL15160766 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL23710842 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL21401388 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL22861696 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 | |
| SCHEMBL21106768 | 0.86 | LMNA (0.43) | LMNAHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219945-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | LMNA 1656/4885HRH4 3886/4885HRH3 3631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.