Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582952 | 0.84 | CASP3 (0.50) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL2591395 | 0.80 | CASP3 (0.55) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL2592274 | 0.80 | CASP3 (0.55) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL2584474 | 0.78 | CASP3 (0.48) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL2582892 | 0.77 | CASP3 (0.52) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL2582895 | 0.77 | CASP3 (0.52) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL14759058 | 0.77 | CASP3 (0.55) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL2583742 | 0.76 | CASP3 (0.53) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL121973 | 0.76 | CASP3 (0.69) | CASP3SENP8SENP7SENP6HDAC6 | |
| SCHEMBL29784233 | 0.76 | TTR (0.72) | CASP3SENP8SENP7SENP6HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011138427-A2 | PYRIDAZINONES AS GPR119 AGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-11-10 | — | — | WO | disclosed |